optimization of clinical target volume delineation using magnetic resonance spectroscopic imaging (mrsi) in 3d conformal radiotherapy of prostate cancer

نویسندگان

m. robatjazi department of medical physics, tehran university of medical sciences, tehran, iran

s.r. mahdavi department of medical physics, iran university of medical sciences, tehran, iran

a.r. nikofar department of radiation oncology, iran university of medical sciences, tehran, iran

b. bolouri department of medical physics, iran university of medical sciences, tehran, iran

چکیده

background: for the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, mrsi was used as a molecular imaging modality with mri and ct images. materials and methods: the images of 20 prostate cancer patients were used in this study. the mr and mrsi images were registered with ct ones using non-rigid registration technique. the ct based planning (bp), ct/mri bp and ct/mrsi bp was performed for each patient. for plan evaluation, dose volume histograms (dvhs) data were used. a paired sample t-test was used for the analysis of the obtained data. results: the percentage of variation of ctvmri to ctvct and ptvmri to ptvct were 12.83% and 8.97%, respectively. ctvmrsi and ptvmrsi were 21% and 27.41% more than their corresponding values of ct volumes. the mean percentage of variation in rectum volume that received 60% of the prescribe dose (v60r) in mrsi/ct bp relative to ct bp was 14.66%. conclusion: the use of mrsi in detecting of prostate adenocarcinoma could provide some decisive information to determine optimum volume and safe margin for target definition to improve adaptive radiotherapy in prostate cancer.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Optimization of clinical target volume delineation using magnetic resonance spectroscopic imaging (MRSI) in 3D conformal radiotherapy of prostate cancer

Background: For the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, MRSI was used as a molecular imaging modality with MRI and CT images. Materials and Methods: The images of 20 prostate cancer patients were used in this study. The MR and MRSI images were registered with CT ones using non-rigid registration technique. The CT based planning (BP), CT/MR...

متن کامل

The Role of MRSI in Target Volume Definition for Radiation Therapy of Prostate Cancer

Introduction: Recently, magnetic resonance spectroscopic imaging (MRSI), as a functional imaging method, has been used for clinical target volume definition. In this study, we used this method to define the target volume in prostate radiotherapy. Material and Method: In this study, we used images of 20 prostate cancer cases. MRSI and MRI images were fused with CT images. Then, treatment plannin...

متن کامل

FDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma

BACKGROUND FDG-PET/CT imaging has an emerging role in staging and treatment planning of various tumor locations and a number of literature studies show that also the carcinoma of the anal canal may benefit from this diagnostic approach. We analyzed the potential impact of FDG-PET/CT in stage definition and target volume delineation of patients affected by carcinoma of the anal canal and candida...

متن کامل

Application of computed tomography and magnetic resonance imaging fusion images for delineating gross tumor volume in three-dimensional conformal radiotherapy of nasopharyngeal carcinoma

Background: To evaluate computed tomography (CT) and magnetic resonance imaging (MRI) fusion images for delineating gross tumor volume (GTV) in three-dimensional conformal radiotherapy (3D-CRT) of nasophanrygeal carcinoma (NPC), and compare treatment outcomes between CT- and CT+MRI-based targets. Materials and Methods: A total of 120 NPC patients treated with 3D-CRT were included, in which, 60 ...

متن کامل

Target volume delineation of anal cancer based on magnetic resonance imaging or positron emission tomography

PURPOSE To compare target volume delineation of anal cancer using positron emission tomography (PET) and magnetic resonance imaging (MRI) with respect to inter-observer and inter-modality variability. METHODS Nineteen patients with anal cancer undergoing chemoradiotherapy were prospectively included. Planning computed tomography (CT) images were co-registered with 18F-fluorodexocyglucose (FDG...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of radiation research

جلد ۱۲، شماره ۴، صفحات ۳۰۳-۳۰۹

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023